Phoebe Sussana PRIMUS

By szehuichan, Mon, 10/19/2026 - 11:03

ChM. Dr.

Lecturer

Office: A4-212

Email: phoebe.sussanaprimus@xmu.edu.my

Research Interests: Natural Products Chemistry, Phytochemistry, Green Extraction and Separation, Molecular Networking

Full Academic Profile

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About Me

Dedicated Natural Products Chemist specialising in phytochemistry, metabolomics, and bioactive compound discovery from medicinal plants. I obtained my PhD in Organic Chemistry from Universiti Malaya and has discovered several bioactive novel natural compounds, including Stenophyllols A-C, Glabraquinones A-B, and a new oxoaporphine alkaloid, unlocking promising therapeutic abilities. I also completed a research internship at Kaohsiung Medical University, Taiwan, on peptide synthesis for bioactive nanomolecular carriers and participated in community outreach with Indigenous communities in Namasia DIstrict, Taiwan. My current research integrates metabolomics, molecular networking and green extraction for sustainable bioactive compound discovery.

PhD in Organic Chemistry (Natural Products Chemistry), Universiti Malaya, Malaysia (2024)
MSc in Analytical Chemistry and Instrumental Analysis, Universiti Malaya, Malaysia (2009)
BSc (Hons) Science Education (Chemistry), Universiti Pendidikan Sultan Idris, Malaysia (2006)

Member, Institut Kimia Malaysia (IKM), M/6691/10724/24

Research Interests

My research focuses on the discovery of bioactive natural products from medicinal plants through the integration of phytochemistry, analytical chemistry, and molecular networking. I am particularly interested in applying advanced spectroscopic and chromatographic techniques and in-silico screening to identify novel compounds with therapeutic potential. Current work explores green extraction and sustainable separation technologies, and metabolomics-driven natural product discovery. My long-term research goal is to advance the valorisation of Malaysian medicinal plants and agricultural biomass as sustainable sources for the development of innovative functional foods and novel therapeutic agents.

Research Project(s)

To be updated

Current Courses Taught

MBT104 – Organic Chemistry and Laboratory
BSC202 – Organic Chemistry Laboratory
FSC202 – Organic Chemistry Laboratory
CME111 – Analytical Chemistry for Engineers

Local Grant(s)

International Grant(s)

Journal

Primus, P. S.*, & Choo, Y. M. (2026). Phytochemical diversity and therapeutic potential of the Polyalthia genus: a comprehensive review. Phytochemistry Reviews. doi.org/10.1007/s11101-026-10257-3 (WOS, Q1)
Primus, P. S.*, & Choo, Y. M. (2025). Phytochemistry and Pharmacological Potential of the Genus Prismatomeris. ACS Omega. 11 (1), 32-45. doi.org/10.1021/acsomega.5c10436 (WOS, Q2)
Primus, P. S.*, & Choo, Y. M. (2024). Phytochemical diversity and therapeutic potential of the Boesenbergia genus: a comprehensive review. Phytochemistry Reviews, 24(5), 4159-4182. doi.org/10.1007/s11101-024-10033-1 (WOS, Q1)
Primus, P. S.*, Wu, C. H. Y., Kao, C. L., & Choo, Y. M. (2024). A New Oxoaporphine and Liriodenine’s Anti-Neuroblastoma Potential from the Roots of Polyalthia bullata King. Sains Malaysiana, 53(2), 359-367. doi.org/10.17576/jsm-2024-5302-10 (WOS, Q3)
Lee, M. Y., Shiau, J. P., Tang, J. Y., Hou, M. F., Primus, P. S.*, Kao, C. L., & Chang, H. W. (2023). Boesenbergia stenophylla-Derived Stenophyllol B Exerts Antiproliferative and Oxidative Stress Responses in Triple-Negative Breast Cancer Cells with Few Side Effects in Normal Cells. International Journal of Molecular Sciences, 24(9), 7751. doi.org/10.3390/ijms24097751 (WOS, Q1)
Primus, P. S.*, Wu, C. H. Y., Kao, C. L., & Choo, Y. M. (2022). Glabraquinone A and B, new bisanthraquinones from Prismatomeris glabra (Korth). Valeton. Natural Product Research, 54, 1-8. doi.org/10.1080/14786419.2022.2147932 (WOS, Q3)
Primus P. S.*, Ismail, M. H., Adnan, N. E., Wu, C. H. Y., Kao, C. L., & Choo, Y. M. (2022). Chemical Constituents and Anti-Neuroblastoma Activity from Boesenbergia stenophylla. Sains Malaysiana, 51(4), 1075-1084. doi.org/10.17576/jsm-2022-5104-10 (WOS, Q3)
Primus, P. S.*, Ismail, M. H., Adnan, N. E., Wu, C. H. Y., Kao, C. L., & Choo, Y. M. (2022). Stenophyllols A-C, new compounds from Boesenbergia stenophylla. Journal of Asian Natural Products Research, 24(2), 146-152. doi.org/10.1080/10286020.2021.1883590 (WOS, Q3)

Conference

Primus, P. S.* (21^st-24^th September 2022). Chemical Constituents and Anti Neuroblastoma Activity from Boesenbergia stenophylla. [Oral Presentation]. International Conference of Natural Products 2022, ICNP 2022. Hilton Hotel, Kinabalu, Sabah, Malaysia.
Primus, P. S.* (2^nd-4^th December 2018). In-Vitro Antioxidant Activity of Boesenbergia stenophylla Rhizomes. [Oral Highlight Presentation]. ASEAN Emerging Researchers Conference 2018, AERC 2018. Sunway University, Petaling Jaya, Malaysia.

Phoebe Sussana PRIMUS